Relief o choking in victims one year of age and older Essay

Relief o choking in victims one year of age and older - Essay Example When there is plenty of nasal secretion in the airways of a child, breathing difficulties may arise during feeding and in the periods between meals, because some children are unable to open their mouths wide enough once their noses are bunged up. As a child in new born, inhalation difficulties are likely to arise, if there is a mechanical obstruction in the airways. Problems with both inhalation and exhalation can indicate cardiac dyspnea in children. Yet, the most common reasons for choking in children aged one year or older include breathing in a small object, a part of a toy, food or some other object that might block airways, i.e. throat and windpipe. It is also possible that children breathe in vomited material, while being asleep/unconscious. Generally, choking in children aged one year and older is caused by the obstruction of a child’s airways, which can be divided into two main kinds – mild and severe airway obstruction (Blair-Harmon). Naturally, handling different kinds of choking depends greatly on recognition of them and knowledge of symptoms. The signs indicating mild airway obstruction are the following: there is a good air exchange in a child’s airways; the child is responsive and coughs forcefully; the child might wheeze between coughs (Blair-Harmon). This type of obstruction is easy to get rid of as there is a good air exchange and apnea is virtually impossible. Thus, it is important to encourage breathing efforts and coughing in children until the foreign object is removed. Moreover, one mustn’t interfere with the attempts to remove the foreign object or perform first aid, yet it is necessary to stay with the child and monitor the situation – the need to call 911 may arise, if mild airway obstruction still persists. Another – and more serious type of mechanical obstruction is severe airway obstruction that is crucial to be recognized promptly. In this case, there is no

Salem Witch Trials Essay Example for Free

Salem Witch Trials Essay Other people say it started on the night of the devouring. The repercussions of this event can still be felt globally. The suspicion of witch craft in Salem Village, Massachusetts began in January 1692 when a group of girls began to act strangely (The Salem Witch Trials, eyewitness to history). The town could not explain the seizures, random screaming, and trance states that affected the girls. The doctors were summoned in to examine the girls but could not find cause of the behaviour. The community reasoned that it must be the work of Satan. Witches had invaded Salem. The girls were given a trial then later were put to death. After this many of the people of Salem were accused of witch craft,some were burned while others were hung (First Salem witch hanging). They were not given fair trial. Nobody was sure where the witch craft started or how it came about but some of the older towns people said that the magic was always there it just had not been activated by the right person yet (Blumburg). They thought that the right person must of came along and that it had to be a new person in town and somebody who had the power of getting other people to help in witchcraft. The only logical person who they could think of that fit this description was Martha Corey. (First Salem witch hanging) The Trial of Martha Corey was on Friday March 11, 1692 it was a day of fasting and prayer in Salem. The accusation shocked those who heard it because Martha Corey (Good wife Corey) was a new but upstanding member of the community. Immediately a somebody was sent to the Corey farm to question Martha hoping to clear her name. Martha Coreys sarcastic response to her being accused caused her immediate arrest. In the courtroom Maratha’s accusers writhed in agony as they were forced by an unseen power to mimic the witchs every movement. When Martha shifted her feet they did too,when Martha bit her lip they were compelled to. On, Monday, the 21st of March,the magistrates of Salem appointed to come to examination of Good wife Corey. And about twelve of the clock they went into the meeting house,which was thronged with spectators. Mr. Noyes began with a very pertinent and pathetic prayer, and Good wife Corey being called to answer to what was alleged against her, she desired to go to prayer, which was much wondered at, in the presence of so many hundred people. The magistrates told her they would not admit it; they came not there to hear her pray, but to examine her in what was alleged against her. The worshipful Mr. Hawthorne asked her why she afflicted those children. She said she did not afflict them. He asked her, Who did then? She said, I do not know; how should I know? † (Lawson) Martha was portraying that she had no clue as to what was going on and that she was being accused of something that she did not do. But if Martha truly was innocent then why would she not pray and why would she not fight and show more passion that she was not a witch. Some of the people in the town started to come forward and telling things about Martha, because they believed she was a witch crop failures or infant deaths -local villagers were quick to accuse each other of witchcraft (Milton). They would say that she has a book of spells and that she tried to convince young girls into doing magic with her, the younger the girls were the easier it would be to harvest their magic. Others would say that she had a little yellow bird that she would put in her hand and kill then she would bring it back to life to show how much power she actually had. Nobody actually had proof that Martha was a witch and that she was in fact practising witch craft. (Salem witch trials) From the late 15th century to the late 18th century a wave of persecution washed across parts of Europe. Tens of thousands of people were executed for witchcraft. But what happened? Belief in magic was almost universal in the past. Almost all cultures believed that you could use supernatural means to help hunting or to make your crops grow better or to make humans or animals more fertile (Lambert). But you could not use magic to heal humans and animals (Lambert). For most people who lived before the 18th century magic was an ordinary part of everyday life. To them the world was a mysterious and frightening place. They did not know what caused diseases and sickness so they would sometimes assume it was something supernatural. The people of the 16th century would use what they thought magic in their everyday lives to try to make things better for themselves , but when people started thinking that humans were using magic on other living things that’s when magic started being considered evil and a bad thing (Lambert). People who believed in magic the thought that your enemies could use magic to harm you was terrifying. Most people in the 16th century believed that God had an enemy called the Devil, who was very powerful. They believed that witches made a pact or agreement with the Devil and agreed to worship and serve him. When people were being accused of witch craft they were not given a fair trial. They did not use evidence they did not give you a voice,if somebody said you were a witch then you must be a witch (Lambert). The history of witch craft is so great that nobody is really sure what actually happened. There are many theories as to what actually happened , some say that witches started coming to earth and taking over human bodies when the devouring night started. On the night of the devouring or otherwise called sorry night, otherwise know as Halloween, is when witches come down from their world and inhabit the people who are scared(Holt). They take over the scared humans because they are alone and have no way of defending themselves , their minds are essentially open and easy to take over(Holt). They take over their bodies and then the witches have a vessel which they can perform their magic from. The witches who take over the human body make it so the human that was already in the body feel like they are asleep. The witch will inhabit your thoughts and your past and they will act like the person they took over as much as they could(Holt). A witch would sometimes slip up and their magic would start to show or they would be caught,in some cases they would get caught without even realizing it. The longer a witch is in a body the harder it would be for their magic if it was evil to start showing. When a witch would get caught performing magic back in the 16th century they had no way to escape the human because the only day they can enter or leave body is on October thirty first or if the human is illed. When human was hung the witch could stay around and inhabit another body but when the body was burned the witch died with it. It took a long time for people to realize what was happening. It was one of the most logical reasons to how witches could come about. (Holt) In some cases female witches were treated a lot worse than male witches were. Female witches were usually beaten and their houses wo uld be raided then burned down they then would be hung or burned and sometimes even both depending on how strong they thought the witch was (Lyons). In rare cases men witches were kept alive because priests would try to save them and get extract their magic so they could use it for their own purposes(Lyons). Once the priests were done with the male witches if they still believed they were witches they would be killed and their belongings would be burned(Lyons). Because of the Salem witch trials , thousands globally lost friends and family members over the suspicion of being witches and doing harm. People would be killed if they were a good witch or a bad witch,innocent or guilty, proof or no proof. If somebody was thought to be a witch then you were going to be killed. A group of people the descendants of people who were killed in the trials , otherwise known as the Salem five started a petition for their ancestors names to be cleared and know that they were not witches and that they were killed when they were innocent (American Heritage). It was a long fight for there names to be cleared but in the end they eventually got their names cleared and they got their names in the paper and their names on the list of people who were believed to be innocent during the trials but they were killed without real proof. American Heritage) When the witch trials were going on witches were thought to have looked like ordinary people who have the power to kill people, make potions, and control people . Witches were thought to be evil and only capable of doing harm, yet they would walk among humans and act like humans in most cases. The witches in the 16th century were though to look like normal everyday humans ,so they they would not have to hide(Salem Witch museum). Now in the 20th century witches are thought to have long stringy uncombed black hair and facial warts with a green face ,and a big nose. They are thought to wear all black and long stocking ,they ride around on broom sticks and have loud cackling laughs. The transition from what people thought use to be witches and what people now think a witch would look like is so different from what they use to be like. The change in what witches look like started when all witches started to be thought of as evil and corrupting. The change happened when parents would tell their children about evil creatures that would take them in the night and make them do things that they would not want to do . People changed the look of witches so that their stories would scare young children. Years of stories being passed down generation after generation people started to forget that witches actually look like normal humans and that they blend in with everyday society. (Salem witch museum) The repercussions of the Salem witch trials effected thousands of innocent people. People were murdered without given a fair trial , many family lines were massacred , and now most people think that all witches are evil and that all the stories about witches are true. Thousands of innocent people , including women and children , were slaughtered globally during the Salem witch trials(Salem witch trials). Many family lines were cut out and killed altogether during the trials. When witch craft was happening in some cases whole families were convicted and then slaughtered , they were not given fair trials because there was no real proof that they were actually witches. After the witch trials were finished all over the world everybody started assuming that all witches were evil and that magic good or bad should not be allowed. Many folklore tales were made up and legends were started to be told all over the globe about evil witch craft ,and how witches take over your body and kill your soul . Some people would say that when witch craft was used for killing humans and animals and manipulating them that is when you would lose your soul. Because of The Salem witch trials thousands of innocent people were killed with little proof , real witches were not killed ,and people were taken over during the devouring. Since the witch trials happened globally many stories and legends were started and there is no real proof as to what happened. Some families tried to get their ancestors names cleared but not everybody who was faultily killed got their names cleared. The repercussions of the trials are still felt today globally. Work Cited (Holt Simon,The Devouring, September 1 , 2008) January Lyons , Diane Witchcraft, gender, power and intimate relations in Mura compounds in Dela, northern Cameroon. EBSCO HOST. May 2 ,2013. Salem witch Museum. http://www. salemwitchmuseum. om/. May 2,2013 Lambert , Tim. The Salem witch trials . Localhistories. com April 26,2013 http://www. localhistories. org/salem. html The Salem Witch Trials, 1692, EyeWitness to History, www. eyewitnesstohistory. com (2000). April 30th , 2013 Salem witch trials. Welcome to Salem Massachusetts. April 24th 2013 http://www. salemweb. com/guide/witches. shtml Blumburg, Jess. A Brief History of the Salem Witch Trials. Smithsonian. com Published October 27th,2007 May 1st 2013 http://www. smithsonianmag. com/history-archaeology/brief-salem. html April 30th 2013 Lawson , Deodat. The Salem Witch Trials,1692. Eyewitness to History. Published in 2000. http://www. eyewitnesstohistory. com/salem. htm April 29th 2013 Milton, Gilies. SALEM WITCH TRIAL: THE CASE OF GILES AND MARTHA COREY published December 12 2012. Surviving-History. blogspot. ca April 30th , 2013 First Salem Witch hanging. Www. history. comhttp[-gt;1]://www. history. com/this-day-in-history/first-salem-witch-hanging April 30th , 2013 [-gt;0] http://ec. tynt. com/b/rw? id=cd5NqsI_0r3Qffab7jrHtBu=SmithsonianMag [-gt;1] http://Www. history. comhttp/

Essay --

Jordan Belfort: Money Outweighing Punishment The stock market is an enigma to the average individual, as they cannot fathom or predict what the stock market will do. Due to this lack of knowledge, investors typically rely on a knowledgeable individual who inspires the confidence that they can turn their investments into a profit. This trust allowed Jordan Belfort to convince individuals to buy inferior stocks with the belief that they were going to make a fortune, all while he became wealthy instead. Jordan Belfort, the self-titled â€Å"Wolf of Wall Street†, at the helm of Stratton Oakmont was investigated and subsequently indicted with twenty-two counts of securities fraud, stock manipulation, money laundering and obstruction of justice. He went to prison at the age of 36 for defrauding an estimated 100 million dollars from investors through his company (Belfort, 2009). Analyzing his history of offences, how individual and environmental factors influenced his decision-making, and why he desisted from crime following hi s prison sentence can be explained through rational choice theory. Jordan Belfort’s exploitation of individuals and the financial system was for solely the purpose of financial gain. Rational choice theory dictates that individuals are of rational minds and will calculate the costs and benefits and choose actions where the benefits outweigh the punishment for committing it. This theory explains why Belfort turned to criminal actions, such as market manipulation, fraud, and money laundering over normative actions to achieve his goal of wealth when his greed outweighed any fear of punishment from the justice system. Rational choice theory, developed by Ronald Clarke and Derek Cornish in 1985, is a revival of Cesare Becca... ... desisted from crime as his calculations of probability of punishment offsets any potential rewards and thus deterrence is created. Jordan Belfort throughout his entire life subverted the law for his own financial gain, always seeing money as worth the risk in the decisions he made. His decisions were made by a rational mind of his own volition, considering the long-term possibilities and how to stay ahead of his pursuers. He constructed an environment with Stratton Oakmont to enable this behaviour, as well as corrupt those around him to follow in his footsteps. This lead to his repeated violations of laws to generate wealth when his fear of punishment was lower than that of the rewards he could potentially gain. It was only when he was confronted with the reality of his punishment and experienced it directly that he was finally deterred from his criminal behaviour.

Havisham

The ideas the Duffy is trying to convey is the idea the heart brake and physiological damage of a relationship gone corrupt and by a wedding day that was a- boarded ND the devastating impact on the bride who was left standing on her own embarrassed and humiliated by the failure of her beloved to show up. The idea of society expectation has also shrouded upon her since she can't even leave her own house since she is paranoid about society expectation of a classic woman.Society expects a woman to find a man and get married and have children and by her not fulfilled society's expectation she has â€Å"failed† at life's virtue for a woman therefore having a unworthy life by living as a â€Å"spinster† and wasting away thou a husband. Another idea conveyed is the effect of also being alone without a partner â€Å"a lover† to share your life with. This is reflected by Ms Having who has always been alone and never really had â€Å"true love† and the effects of th at how our feelings can go to mutual hatred towards one person whom in their mind destroyed their entire life.The poem is titled Having and not Miss Having. Why? The poem Is titled â€Å"Having† opposed to â€Å"Miss Having† since she doesn't have the honor being labeled a â€Å"miss† due to turning Into a complete monster. She Is not a lady , she's not proper or has the correct virtue for a typical ladles life. She Is an old hag who has wasted away and is nothing more than to be called a spinster. Having creates a harsh , violent and bold statement reflecting her and everything he's become.Where as Miss creates a peaceful , calm and relaxed tone and doesn't reflect her at all. What do you think the poem gains from the images of violence in it? The poem advances with Images of violence from the text since it creates an image of his woman and the extent of her despair and trashed life that took a turn Off cliff and died. The metaphors and imagery shown In the tex t such as † so hard Vive dark green pebbles for eyes† really gives the audience an Intense Image and shows how she hardened from the Inside and has nothing but venom filled In her veins. Opposition. The feelings of Ms Having are mixed due to the confusion inside and the baffling she's had to deal with to come to terms with the â€Å"tragedy'. The feeling consist o darted and evil towards this man shown through † wished him dead† hating this man so much to the extend she wished death upon him. Feeling stretching to her love for him expressed minimally for example † Beloved sweetheart† showing a more inmate and loving tone.Then creating a more somber tone with the loneliness she has by herself â€Å"give me a male corpse for a long slow honeymoon† showing the extend that she wants someone this man so bad that she would replace him with a male corpse since she realizes that no man would ever want her. The reason for these binary opposite is s ince that is what we as humans feel mixed emotions , churned up together creating confusion fore her and us. Sometimes the persona imagines the passionate times she could have had with her lover.Which part of the poem describes this? The poem describes the time she could have had with her lover are shown in many instances like † the dress yellowing† expressing that she has waited for him all these years and that they still could get married and have a fulfilled life together. This is also shown through â€Å"give me a male corpse for a long slow honey moon† expressing that they had the opportunity to go on a beautiful honeymoon together.To what extent does the poem reflect a feminist agenda, or even Duffy own feelings at the time of writing? Address the attitudes and values conveyed. To a minimal extent the poem reflects a feminist agenda since the poem is directed towards her lover but is shown in some instances like â€Å"loves hate behind a white veil† h ere the feminist agenda is reflected is the quote since it undermines the institution of arraign and the idea that it is not worth it , a disappointment and alluding to gay and lesbian rights.Another references is shown through â€Å"spinster† since the meaning of the word is a old had and unmarried wasting away without a husband. Hence showing the inequality between men and woman since the term for a unmarried man is â€Å"bachelor† which is viewed in a positive light and being a good thing whereas woman are considered a disappointment by not get married therefore highlighting the feminist agenda. Havisham The opening line portrays the order of events. â€Å"Beloved sweetheart bastard. † The man she describes was someone special but soon became someone she hated. She has longed for revenge as the reader is told, â€Å"Not a day since then I haven't wished for him dead. † The words â€Å"prayed† also tie in with this deep seated longing for change. The imagery of her eyes being like â€Å"Dark green pebbles† hints to the hardness of stone but also the green is jealousy. She has become trapped by obsession: thinking, praying and waiting for her fiance. The word â€Å"Spinster† is a one word sentence, almost spat out in distaste. Havisham describes her condition â€Å"I stink and remember† the words refer to her smell from wearing the same clothes but also the stench of the terrible thing that has happened to her. The events have changed her and there is real sadness and fear behind the words. Her wedding dress is described as â€Å"yellowing† as she questions how she has ended up in this situation. The final part of the previous stanza merges into this third verse and the disjointedness reflects Havisham's own distress. This stanza hints that sometimes she can feel happy and when she is bed asleep for a moment it as if she is still with her lover, but the strong words â€Å"bite awake† describe the gnawing pain of having lost a loved one. The dream is only a dream and life is difficult to live with. Love is personified and the narrator describes herself as â€Å"Love's hate behind a white veil† Love enjoys hurting her and again this is emphasised with her description of the balloon â€Å"bursting in my face. † Balloons are supposed to be fun like love but in this instance it becomes something shocking ready to spoil her happiness. Havisham also describes at destroying her wedding cake, â€Å"I stabbed at a wedding-cake. † This describes not only her pain, but the pain she would like to inflict on someone else. The imagery of a honeymoon is coupled with the words â€Å"male corpse† this also shows her unfeeling towards men. She doesn't want something living, she wants something dead. The very last word comes out in a stutter when she talks about how a heart â€Å"b-b-b-breaks† this shows sadness and madness at the same time. When she talks about her heart not being the only one that is broken it reminds us of Pip from â€Å"Great Expectations†, she's been hurt and knows how to break a man's heart. In the case of Pip, she wanted to crush his dreams of gaining an education.

Ambush Marketing- Is It Ethical

Ambush Marketing- Is It ethical? While a lot of discussion has been going on for quite some time on â€Å"Marketing ethics† including almost every aspect of marketing be it market research, market audience, pricing or marketing strategy. But none of these issues seem to be even close to the issues raised by the ethics of advertising and promotion and specifically â€Å"ambush marketing† in particular. Hence in this article we will take a quick look at the ever-increasing practice of ambush marketing, its origin, examples and its ethical concerns. Background: The term â€Å"ambush† in literal terms means â€Å"an attack from a hidden position†, this in fact, is the founding stone of the term â€Å"ambush marketing†. â€Å"Ambush Marketing† was coined in the 1980’s by Jerry Welsh, the renowned marketing strategist, while he was working as a manager for global marketing efforts for American Express. When he coined the term, he referred it as a creative and legitimate marketing strategy which could provide a level playing ground to the competitors of a thematic sponsor. Today, however, the term is associated with a negative connotation. According to Wikipedia â€Å"ambush marketing refers to a company's attempt to capitalize on the goodwill, reputation, and popularity of a particular event by creating an association with it, without the authorization or consent of the necessary parties. † It is an attempt of the ambusher to associate itself with an event without paying the fee and get some rub-off effects from it. When implemented effectively, it diminishes the value of the actual sponsors of the event by confusing the customers Fig:Typical example of ambush marketing Fig1. :Jet airlines putting a billboard â€Å"we’ve changed† Fig1. 2:Kingfisher took the responsibility of making them change Fig1. 3:Go Air cashed in on the success of the two billboards There is a thin line between Ambush marketing and effective marketing practice. All the marketing strategies adopted by a rival company in the midst of an event cannot be called as ambush marketing. An activity is termed as ambushing only if the m arketer is trying to endorse a specific product/event and by doing that the revenues of the main event are getting damaged. For example f spice jet shows its commercials in between a motor sports event, it will not be guilty of ambushing. But if Pepsi is launching a new ad campaign in between cricket world cup whose official sponsor is coke and it affects the sales of coke, it will be termed as an instance of ambushing. Fig:Pepsi ad during 1996 WC Strategies for ambush marketing can be broadly classified into two groups: Forging: In this form, a company misleads the people that the ambusher is one of the sponsors of the event by using a similar name or logo associated with the event while it is not. For example, in 2002 Sydney Olympics, Quantas airlines changed its slogan to â€Å"The spirit of Australia† which was very close to the games slogan â€Å"Share the Spirit†. This was a classic case of ambush marketing as the official airline partner of the event was Ansett Air but the slogan of Quantas airlines suggested otherwise. Fig:Quantas airlines Intrusion: Here the ambusher tries to give its own name or trade mark through the medium of publicity of the event without seeking the permission of the organiser. This strategy uses the attention created by the event to promote the ambusher’s product. This strategy is more popular with the ambushers now-a-days as forging can lead to legal actions and this is comparatively a risk-free strategy. A notable example of this strategy was in 2002 Boston Marathon, whose official sponsor was Adidas but Nike provided the runners with spray painted â€Å"swooshes† which suggested that the event was sponsored by Nike. Fig:2002 Boston Marathon In 2006 Bavaria Brewery gave away orange overalls called Leeuwenhosen to some of the fans to support the Netherlands football team with the brewery’s logo on them. The FIFA officials asked the fans to remove the orange overalls as Budweiser was the official sponsor. Fig: Supporters wearing Leeuwenhosen By this time you all must have guessed the issues with ambushing, but then too let us reiterate some of the important ones. The first and the biggest of them is that it reduces the effectiveness of the advertisements of the original sponsors of the event and decreases their revenues. It can also lead to withdrawal of some of the sponsors from the event such as IBM and Mars from the Olympic TOP programme. The sponsorships for these events are costly and by ambushing, these companies are deprived of their right to increase their visibility and thereby their customer base. Remedies for Ambushing: Ambushing has been gaining popularity ever since it came into existence which is causing a lot of concerns for the official sponsors of the event. Hence for better protection of the interests of the company certain strategies have evolved which could help the victim company to counter ambushing. The major ones are Learn How to Ambush: This measure is based on the premise that if the knows how to ambush then it will also know the vulnerable points on which it could be ambushed and then it can try to plug those gaps through stringent contracts. Leveraging: These are supplementary measures such as ads aimed at increasing public awareness about the official sponsors of the event. Limit a non-sponsors capacity to advertise: By limiting the non-sponsors ability to advertise in the proximity of the event reduces the probability of ambushing through physical stalls, outlets etc. This strategy is also known as â€Å"clean stadium† policy. Establish more control over advertising: This is one of the most important and one of the most difficult measures to exercise. Since reach of media to the viewers of an event is much more than the people actually coming and watching those events, it is very important for firms to try and limit the advertisements by non-sponsors. Educate Consumers: One of the most safest and effective measure is making the customers known about the official sponsors so that the ambushers cannot mislead the public. Legal Restrictions: Stringent legal measures can act as deterrents to the practice of unethical ambushing. Is it ethical? Ambush marketing has changed its shape and form from 1980’s till today. But what is constant is the debate on whether it is ethical or not. The answer is very subjective. If you are asking this question to the sponsor of the event he might say that it is synonymous with crime and to an ambusher it might seem to be an intelligent marketing strategy. The viewpoints become completely reversed if the ambusher is made the sponsor and vice-versa. My opinion about ambushing is same as the ambushers. Marketing as a field of study has always been associated with creativity and ambushing gives them a perfect platform for the same. In today’s world, where there is cut throat competition between corporates due to increasing competition and reducing margins, companies have to come up with such kind of measures to counter other. During the times of recession, when all the major economies of the world go to a standstill, it serves as a cost effective method of advertising. For me it is not breaking the law or doing illegal, it is an intelligent use of the loopholes in the marketing practices of the other firm. If my rival is not aware of its shortcomings, I should use it to my advantage. Also, competition is not a game with set rules; if I am refraining from using ambush marketing today does not mean that my rival facing the same condition would not use ambush against me. In my viewpoint, it is one of the best methods of marketing involving minimum capital and maximum gains. What you think of ambushing is up to you to decide.

Medical Anthropology Paper-Tay Sachs Disease Essay Example

Medical Anthropology Paper Medical Anthropology Paper-Tay Sachs Disease Paper Medical Anthropology Paper-Tay Sachs Disease Paper A normal infant has the ability to develop healthy motor functions due to the synthesis of certain enzymes vital for clearing harmful materials that can interrupt the growth process. However, babies that inherit the gene coding for Tay-Sachs disease experience motor function disorders. Tay-Sachs disease is a rare genetic disorder inherited by individuals that causes the degradation of their central nervous system. This condition is not treatable. Moreover, it progresses continuously from infancy until early childhood, a point where the patient fails to survive. The disease occurs within a defined population, commonly found among eastern European Ashkenazi Jews. The said disorder results from genetic mutations whose effects are manifested from infancy and are highly fatal for affected babies. In addition, it is acquired through genetic inheritance and is detectable prior the childs birth (Lowden 575). The disease is due to a mutation at chromosome number 15 which results in a dysfunction of the lysosomal enzyme acid hydrolase. Deficiency of Beta Hexosaminidase A is characteristic among afflicted patients. This enzymatic absence can be attributed to the occurrence of a founder effect, which accounts for the unusually high frequency of an allele that is an identical copy carried by the individual who founded the population (Slatkin 282). Currently, there are neither treatments nor drugs that would cure Tay-Sachs disease. However, studies have shown that it is possible to prevent the manifestation of Tay-Sachs among potential patients. This leads to the interests of researchers in screening for the probability of passing this disease from heterozygous parents to offspring (Lowden 575). History The disease derived its name from a British ophthalmologist named Warren Tay (1843-1927) and an American neurologist named Bernard Sachs (1858-1944). Tay first provided the characteristic description of retinal cherry-red spot in the eyes while Sachs provided the earliest descriptions of the cellular modifications occurring among afflicted patients. It was also Sachs who first concluded that this disorder is acquired through inheritance from parental genes through studies conducted among numerous patients. His research revealed that this disease notably occurs among Ashkenazi Jews of Eastern European origin (www. ntsad. org). In the year 1900, Sachs collaborated with Dr. Isadore Strauss, who then served as Mount Sinais director of pathology. Their concerted work provided additional descriptions of Tay-Sachs patients, which included observations on the diseases neuropathology. By the middle part of the 1920s decade, Mount Sinai Hospital had finally established a laboratory for neuropathological studies headed by Dr. Joseph Globus. Through this program, scientists were able to identify that autonomic neurons in bowel mucosa are involved. This was used as a diagnostic test, as direct enzymatic assays were not yet discovered. These observations were highly used in determining Tay-Sachs cases and other associated genetic disorder â€Å"through the use of morphological studies of rectal biopsies† (Desnick and Kaback 18). Succeeding years relatively added few descriptions on the morphology of Tay-Sachs disease. But with the onset of the electron microscope during the 1960s, Terry and Korey were able to find numerous bodies bounded by membranes in the cytoplasm of neurons of patients with Tay-Sachs disease. The researchers used a formalin fixed brain specimen, where the tissues were poorly preserved. But the granular bodies that they detected were consistent with brain tissues that were not previously fixed in formalin but immediately placed in a frozen state. In 1963, Terry collaborated with a researcher named Weiss and their studies revealed that the disease is characterized by these granular bodies in the neuronal cytoplasm. Their research team discovered the nature of the lipids that accumulate within neurons, microglial cells, and pericytes. According to their biochemical findings, these deposits possess a ganglioside nature (Desnick and Kaback, 22). Also during the 1960s, an enzyme assay test was developed by Kaback in order to screen heterozygous individuals carrying the allele for Tay-Sachs disease. This test was proven reliable, as it statistically demonstrates low percentage of errors and false positives. The test historically started the determination of potential genetic diseases among offspring. This is essential in preventing diseases and eventually leading to close eradication of the disease among Ashkenazi Jews. Now, it is possible to identify whether couples are at risk in having a child afflicted with the disease (Kaback 255). These efforts of Kaback, together with his team, led to the mass screening of potential disorders among individuals. This program was carefully organized and on May of 1971, approximately 18, 000 adults with Ashkenazi Jewish descent volunteered to be screened for possible heterozygosity. The said screening proved efficient and accurate in determining populations which are potentially at risk. In addition, the screening lasted and from 1969 until 1998, a total of 48,864 heterozygotes were already screened (Kaback 256). Clinical Description The degree of severity of Tay-Sachs manifestation can vary depending on the type of disease. An autosomal recessive disease, Tay-Sachs can cause â€Å"paralysis, dementia, and early death to a chronic adult form† (Genes and Disease 23). These adults afflicted by Tay-Sachs typically manifest psychosis and even neural dysfunction (Genes and Disease 23). Other manifestations of this disease include blindness and deafness early in life. Babies born with Tay-Sachs disease may develop normally during their first 3-6 months, but would eventually deteriorate mentally. They experience delay in mental progression as they experience loss of motor abilities. By the end of their first 12 months, patients rapidly regress mentally and physically. They are exposed to complications in swallowing, as well as in chest, and lung functions (Hauser 2171). Symptoms of this disease include cherry-red macular spots (see Figure 1), or a highly pronounced macular fovea centralis, and an enlarged heart. Babies with this genetic disorder experience disabled motor skills as they could poorly manage to control their heads, fail to crawl, sit and develop visual attention. They also characteristically assume a position that resembles those of frogs. Babies, supposedly at the stage of rapid development, lose their ability to maintain focus and eye contact, when Tay-Sachs starts to manifest. They also exhibit declining environmental interactions while gradually becoming unresponsive. They also develop inattention towards external stimuli until they reach a state that otherwise described vegetative. Hyperacusis, seizure, and macrocephaly are typical of Tay-Sachs disease (Kasper et al. 2318; lysosomallearning. com). There are three forms of Tay-Sachs disease. This includes the classic infantile, the juvenile form, and the adult form. Infants afflicted with Tay-Sachs do not produce Hexosaminidase A, while adults with this disease produce minimal enzymatic levels. Babies born with this disease experience both paralysis and muscle atrophy by six months of age and do not survive longer than five years. Most common ages when children manifest juvenile Tay-Sachs disease are those from 2 to 10 years old. The symptoms of patients are comparable to those with classic infantile form, but with a slower process. They develop dysarthria or speech problems, dysphagia or swallowing complications, ataxia or imbalance, and even spasticity. Patients generally die by their 15th year of age. The effects of the adult version are relatively milder than the classic infantile form, which attributes to their late onset in life. These individuals are otherwise known to possess chronic Tay-Sachs disease. Those with the adult-onset Tay-Sachs disease usually manifest symptoms by their adolescent stage, but it is also possible that these appear during childhood. Unlike babies with Tay-Sachs disease, adults with this disease do not experience blindness or deafness. Although the motor abilities are not completely degenerated, these individuals continuously experience mental weaknesses, including comprehension and memory problems. But different cases present various severity, as some can exhibit â€Å"slurred speech, muscle weakness, muscle cramps, tremors, unsteady gait and sometimes mental illness† (marchofdimes. com). Persons afflicted vary in life expectancy and some may not even to demonstrate the disease. Doctors determining the presence of this disease in individuals must consider investigating the following. Erythrocyte content of both carriers and afflicted individuals are considerably lower concentrations of sphingomyelin. Also, using the enzyme assay, serum or other cell cultures without or with less activities of Hexosaminidase A are a significant consideration. If these tests demonstrate abnormalities, then a DNA analysis must immediately be conducted. This is highly beneficial in determining other members of the family that are heterozygotes for this disorder. This has important implications in child-bearing options of couples and in diagnosing the disease prior a child’s birth. MRI are also commonly used in searching for cerebellar atrophy while electromyelogram is also used in detecting denervation and reinnvervation in individuals with adult-onset of this disease (Tidy; Zaroff 2283). Pathogenesis The most essential organelle involved in Tay-Sachs disease is the lysosome. The biogenesis of this organelle is comprised of different steps synthesizing the following: lysosomal hydrolases, membrane constitutive proteins, and new membranes. The formation of lysosomes is initiated by the fusion of trans-golgi network and late endosomes. With the acidification of vesicles in progression, trans-Golgi network vesicles develop towards maturity. This process creates a gradient that promotes the facilitation of ligand and receptor dissociation. This is highly dependent on the pH levels of the system. Here, lysosomal hydrolases are also activated (Kasper 2318). Any form of interference or abnormalities in these steps of lysosomal biogenesis could result to enzymatic impairment and lead to lysosomal storage disorder. â€Å"Following leader sequence clipping, complex oligosaccharide modification occur during transit through the Golgi, including the mannose-6-phosphate modification of high-mannose oligosaccharide chains of many soluble lysosomal hydrolases† (Kasper 2318). Using various kinds of signals, the lysosomal integral or associated membrane proteins are sorted to the membrane or interior of the lysosome. Concurrently, other processes occur such as phosphorylation, sulfation, proteolytic processing, and macromolecular assembly of heteromers. These are all very crucial steps to ensure the normal functioning of enzymes. Defects of these processes could lead to multiple enzyme or protein deficiencies (Kasper 2318). These mentioned steps are all common for lysosomal storage diseases. But the final pathway is when particular macromolecules, under normal circumstances have high flux of these substrates, within tissues and cells accumulate. When enzymatic deficiency occurs, the most common and major cause are point mutations or genetic rearrangements at a locus that encodes a single lysosomal hydrolase (Kasper 2318). These consequently result in diseases that are passed on from one generation to another. An example of lysosomal storage disorder is the Tay-Sachs disease. This complication is considered an autosomal recessive disorder that is acquired through genetic inheritance. A lysosomal acid hydrolase, ? -N-Hexosaminidase A is a heterodimer composed of alpha and beta subunits. A point mutation occurring at the ? -chain subunit results in an enzymatic deficiency of ? -N-Hexosaminidase A (Myerowitz 3955). The disorders that arise from the mutation of the alpha subunit cause the dysfunction of ? -N-Hexosaminidase A activity. This also includes the abolition of the alpha and beta isozyme activities through the action of the remaining beta subunit (see Figure 2). Tay-Sachs disease is described as one of the earliest versions of human genetic sphingolipidoses where patients suffer from the accumulation of GM2-monosialoganglioside in neurons due to the mentioned ? -N-Hexosaminidase A deficiency (Ohno and Suzuki 18563). The comparison between a healthy neuron and a neuron affected by Tay-Sachs disease is illustrated in Figure 3. The abnormality of the ? -subunit can be attributed to the major deletion found at the 5 end of the gene coding for ? -N-Hexosaminidase A ? chain. It was also discovered that in the coding sequences of ? subunits in relatively mature stages, point mutations occur that consequently result to the synthesis of unique enzymes of GM2-gangliosidosis. In cases of Ashkenazi Jews, patients were observed to possess splicing defects located at the 5 end, where intron 12 is usually donated. This splicing complication was described by employing methods such as cloning, genomic sequencing, and identification of abnormal cDNAs (Ohno and Suzuki 18563). Tay-Sachs is actually a â€Å"group of disorders† (Myerowitz 3955) with varying degree of severity and biochemical parameters. Severity ranges from mild to fatal while the parameters include â€Å"residual enzyme activity, immunoprecipitable ? -chain polypeptide, and detectable ? -chain mRNA† (Myerowitz 3955). These mentioned variations are part of differential ? -chain genetic lesions. In the case of Ashkenazi Jews, this disease has a single clinical course that leads to early childhood death and same biochemical profiles. Scientists hypothesized that the severe form of this disease is caused by a single mutation (Myerowitz 3955). It has been established that Tay-Sachs is the result of accumulation of Ganglioside GM2 due to the cells inability to degrade these granular bodies. In the absence of GM2 activator protein, â€Å" the GalNAc and NeuAc in GM2 are refractory to hexosaminidase A and sialidase respectively† (Li et al. 10014). In the study, it was found that in analyzing the conformatino of these GM2, a rigid and compact structure of the oligosaccharide head group was revealed. This is concluded to be the factor responsible for the resistance of GM2 from degradation or enzymatic hydrolysis (Li et al. 10014). All these abnormal processes are primarily attributable to mutations that occur on chromosome 15. Mutations include insertions and deletions of different base pairs, splice site mutations, point mutations, and other forms. With every modification resulting from mutation processes result in the alteration of the protein or enzymatic product, which causes the inhibition of its function. One of the most commonly observed and noted mutations are those of the Ashkenazi Jews where four base pairs are inserted in exon 11. The result is the classic infantile Tay-Sachs disease that can also be found in other ethnicities (Ohno 18563). Etiology This disease is commonly passed on from carrier parents to their offspring. Children that possess both alleles for Tay-Sachs manifest and suffer from the disease. The human body is composed of 23 pairs of chromosomes, therefore 46 chromosomes in total. These chromosomes contain genetic instructions that always come in pairs, from both maternal and paternal inheritance. But when these genes experience alterations or any form of modification, a mutation occurs and the gene loses its normal functions. Since each individual has two chromosomes, those with only one copy of the dysfunctional gene will be able to continue to function correctly as the normal gene would compensate for the impairment of the other. But if an individual acquires two recessive alleles, the individual will manifest the symptoms characteristic of the disease (Branda et al. 174; www. dnadirect. com). In cases when both parents are heterozygous for the Tay-Sachs gene, there is a 25% probability of passing the disease to the offspring, while a 50% probability of bearing a carrier individual and a 25% chance of a phenotypically and genotypically normal child (see Figure 4). In situations when only one parent is a carrier, there are 0% chances of having an afflicted child. However, they still have a 50% risk of having an offspring carrying the gene for Tay-Sachs (Branda et al. 174; www. dnadirect. com). Epidemiology Tay-Sachs disease is one of the most renowned genetic disorders associated with a certain population. This is a metabolic disorder typically acquired through genetic inheritance and occurs most frequently among Ashkenazi Jews of Eastern Europe. However, the disease is not confined within this group as it is also found among French Canadians that inhabit the South-eastern portion of Quebec and among Cajuns that live in the South-western part of Louisiana (Genes and Disease 23). One of the causes that scientists propose on the emergence of this disease is founder effect. Founder effect is a potential cause for a high frequency allele within a population in isolation. This is the case if the allele selectively remains in neutrality and if it has identical copies of the original carrier that founded the subpopulation. This is also applicable in conditions where an allele simply arose by later mutating (Slatkin 282). In explaining the phenomenon of the occurrence of high frequency alleles, experts have always employed this founder effects hypothesis. Most disease associated alleles are likely to be non-neutral. However, even alleles with mild deleterious effects could gain high levels of frequency due to founder effects. Today, another explanation is widely accepted in the scientific community in accounting for Tay-Sachs disease. This is the heterozygote advantage. This hypothesis is basically supported by the fact that most disease associated with alleles result from sphingolipid storage dysfunction. This outcome is not commonly observed in the general population. These two hypotheses were highly acknowledged prior the 1990s. But until recently, the heterozygote advantage was questioned and the founder effect has gained a relatively greater acceptance. This is due to several research studies conducted that argued in favour of founder effects as the actual cause of lipid storage diseases in the Ashkenazi Jewish population. The heterozygote advantage is unlikely as some non-lipid storage diseases (NLSDs) are due to dominant instead of recessive alleles and that these NLSDs do not benefit from the presence of disease associated alleles (Slatkin 282). The study on the debate between genetic drift and selection were further investigated by Risch et al. (p. 812). It has been established that Ashkenazi Jews have higher tendencies to acquire lysosomal storage diseases (LSDs), and in this study, four were found to occur at high frequencies. It was suggested that this condition is a result of having natural selection, otherwise termed as carrier advantage, as an impetus. The researchers compared the LSDs and NLSDs in terms of their levels of mutations, allelic frequency distribution, and mutation coalescence dates. It was found that there were no differences in the distribution nor any regular distribuion patterns were observed between LSDs and NLSDs occurring in different geographic areas. But the scientists discovered a more interesting concentration of two particular Tay-Sachs mutations in central and eastern Europe. Such an observation is an indication that genetic drift or the founder effect is the driving force that affected the population. It is the primary determinant of the genetic mutations that occur in Ashkenazi Jews (Risch et al. 812). Treatment and Screening An effective treatment or cure is currently not available for Tay-Sachs disease. Due to this, scientists are exploring on various possibilities that would enable them to formulate the appropriate treatment and management of this disease. Through intensive research projects using therapeutic approaches and clinical trials, experts have discovered a potential cure. This is by employing enzyme replacement therapy in order to compensate for the deficiency of ? -N-Hexosaminidase A absent among afflicted infants and even among adult patients. But this proposal entails several complications as it can affect the brain neurons that receive protection from the blood-brain barrier. Other current studies include gene therapy, pharmacological chaperone therapy, and neural stem cell therapy. Another alternative research is conducted on stem cell transplantation employing the blood of umbilical cord, but all these mentioned potential cure are still under the process of scientific research (www. nstad. org). These stem cell research studies investigate the potential of transplanting bone marrow in treating classic Tay-Sachs disease. These stem cells are immature cells that can differentiate into any form of cell (see Figure 5). In this case, scientists are seeking to produce blood cells from these stem cells either from a bone marrow donor or umbilical cord blood. But this remains unsuccessful in causing the reversal of brain damage that is fatal for afflicted patients. Drug options are also being explores by medical experts, which includes the miglustat drug. This has the ability to cause fatty build up reduction in the brain cells of Tay-Sachs disease patients (Escolar et al. , 2; Bembi 278; marchofdimes. com). The enzyme replacement therapy proposal is basically applicable to most lysosomal storage disorders. The objective is to perform an enzymatic replacement, a procedure comparable to that of injecting insulin to diabetics. The problem in this procedure is that HEXA enzymes are relatively too large to penetrate the blood-brain barrier. This causes the development of blood vessel junctions in the brain, which leads to neuronal cell damage. Alternate pathways were also tested such as injecting the enzyme to the cerebrospinal fluid, but this treatment is still left ineffective (www. freepatentsonline. com). As mentioned in the historical background of this disease, screening for potential carriers is very essential in preventing the manifestation of Tay-Sachs. This is very vital for populations such as Ashkenazi Jews, French Canadians, Louisiana Cajuns, and even Pennsylvania Dutch. This procedure is recommended to be conducted prior conceiving an offspring. But even after the end of an individuals childbearing years, it is still important to be screened for ones status as a carrier as it would make a tremendous difference in the lives of immediate family and close relatives (www. nstad. org). Prenatal tests are currently available such as amniocentesis and chorionic villus sampling. These tests determine the existence of the disease prior a childs birth. Typically conducted between the 15th and 20th week of pregnancy, women can choose amniocentesis where a needle is inserted to the mothers abdomen to obtain amniotic fluid samples. Fetal cells are contained within this fluid and therefore can be tested whether they possess ? -N-Hexosaminidase A. Another test usually conducted between the 10th and 12th weeks of pregnancy is CVS. This is done through the retrieval of placental cells either through tube insertion on the vagina or needle penetration through the maternal abdominal area. Again, the objective is to obtain fetal cells that would be tested for the presence of ? -N-Hexosaminidase A. If these tests reveal the absence of ? -N-Hexosaminidase A, the infant will eventually manifest the classic Tay-Sachs disease. These tests are currently being offered especially to couples who are positive for carrying the allele, and most often to those who resort to in vitro fertilization (www. marchofdimes. com). Conclusion One of the clinical considerations of this disease is that it is caused by an organelle dysfunction, particularly lysosomes. Most cells have a limited life span and therefore must be continuously replaced. Without the proper amount of lysosomal enzymes as typically attributable to a genetic disorder, the result is an abnormal accumulation of glycogen and lipids that could destroy the tissue. This case is demonstrated by Tay-Sachs disease, together with other disorders such as Gauchers disease and glycogen storage. Due to this accumulation, myelin sheaths are destroyed which would lead to the different clinical manifestations of Tay-Sachs disease. (Van de Graaff 370). The Tay-Sachs gene occurs one in every 30 Ashkenazi Jews, making almost 3% of this population as carrier of this disease. Due to lysosomal storage dysfunction, the individual becomes deficient of an enzyme called Hexosaminidase A, which codes for the metabolism of lipid molecules in cellular systems. This fatal neurodegenerative disease has an infantile form and manifests through symptoms such as macrocephaly, loss of motor skills, increased startle reaction, and a macular cherry red spot. Patients exhibiting ataxia and dementia, the juvenile-onset form of Tay-Sachs causes the death of afflicted individuals between ages 10 and 15. The adult onset of this disease is characterized by â€Å"clumsiness in childhood, progressive motor weakness in adolescence, and additional spinocerebellar, lower motor neuron symptoms, and dysarthria in adulthood† (Kasper 2318). Patients commonly demonstrate psychosis and their intelligence continuously declines. Bembi, B. â€Å"Substrate Reduction Therapy in the Infantile Form of Tay-Sachs Disease. † Neurology, 66 (2006): 278-280. Branda KJ, Tomczak J, Natowicz, MR. 2004. â€Å"Heterozygosity for Tay-Sachs and Sandhoff diseases in non-Jewish Americans with ancestry from Ireland, Great Britain, or Italy. † Genet Test 8 (2004):174-180 Desnick, R. , and Kaback, M. Tay-Sachs Disease. Ed. USA: Academic Press, 2001. â€Å"Tay Sachs Disease. † 29 January 2008 dnadirect. com/patients/tests/ashkenazi/tay_sachs. jsp. Escolar, Maria L. , Michele D. Poe, James M. Provenzale, Karen C. , Richards, M. D. , June Allison, R. N. , Susan Wood, P. N. P. , David A. Wenger, Daniel Pietryga, Donna Wall, Martin Champagne, Richard Morse, William Krivit and Joanne Kurtzberg, M. D. â€Å"Transplantation of Umbilical-Cord Blood in Babies with Infantile Krabbes Disease. † The New England Journal of Medicine, 352 (2005):2069-2081. â€Å"Compositions and method for treating lysosomal storage disease. † 30 January 2008 freepatentsonline. com/6066626. html â€Å"Cord Blood. † 4 February 2008 cordbloodusa. org/articles-a1-Cord_Blood. htm. â€Å"Genes and Disease. † Bethesda (MD): National Library of Medicine (US), NCBI. 29 January 2008 ncbi. nlm. nih. gov/books/bv. fcgi? rid=gnd. section. 238. Hauser SL, Longo DL, Harrison’s Principles of Internal Medicine. Ed. 14th ed. New York: McGraw-Hill; 1998; p. 2171. Kasper, D. L. , A. S. Fauci, D. L. Longo, E. Baraunwald, S. Hauser, S. L . Jameson, Harrison’s Principles of Internal Medicine 16th Ed. USA: McGraw-Hill Companies, Inc. 2005. Li, Y. , S. Li, , A. Hasegawa, H. Ishida, M. Kiso, A. Bernardi, P. Brocca, L. Raimondi, and S. Sonnino. â€Å"Structural basis for the resistance of Tay-Sachs Ganglioside GM2 to enzymatic degradation. † The Journal of Biological Chemistry, 274:10014-10018, 1999. Lowden, J. A. â€Å"Role of the physician in screening for carriers of Tay-Sachs disease. † CMA Journal 119 (1978):575-585. â€Å"Tay-Sachs Disease. † 29 January 2008 marchofdimes. com/professionals/14332_1227. asp. Myerowitz, R. â€Å"Splice junction mutation in some Ashkenzi Jews with Tay-Sachs disease. † Natl. Acad. Sci. USA, 85 (1998):3955-3959. â€Å"National Tay-Sachs and Allied Diseases Association. † 29 January 2008 ntsad. org/. National Eye Institute. 4 February 2008 nei. nih. gov/resources/eyegene/redeye. jpg Society for Neuroscience. 4 February 2008 sfn. org/SiteObjects/published/0000BDF20016F63800 FD712C3158BA55/0000BDF200000

The Great Gatsby Quotes Example

The Great Gatsby Quotes Example The Great Gatsby Quotes – Coursework Example The Great Gatsby Quotes and My Interpretation of Its Meaning â€Å"I hope she’ll be a fool- that’s the best thing a girl can be in this world, a beautiful little fool. â€Å" This dialogue was spoken by Daisy in description of her newborn daughter. The social environment that the child was destined to grow up in did not believe that women were capable of any intelligence and the women grew up believing it. I found it quite sad that Daisy made such a comment. Mostly because it solidified the sadness and boredom she felt in her life. Even sadder was that she never tried to challenge the norm of the time even though she had the potential to. It pained me to read how she had to convince herself that she should be happy with the way her life was going and that she was pretending to be what she was not in order to fit in with the societal norm of the time. â€Å"That’s my Middle West . . . the street lamps and sleigh bells in the frosty dark. . . . I see now that this has been a story of the West, after all- Tom and Gatsby, Daisy and Jordan and I, were all Westerners, and perhaps we possessed some deficiency in common which made us subtly unadaptable to Eastern life. â€Å" The use of places to embody themes, characters, and values in The Great Gatsby is a constant method the author used to depict the lifestyle of the characters. While the east is known for the high social life, the midwest, was known for more traditional moral values. This was the moment in the story when Nick realized that he would never fit in where he was because of the differences in values. A realizatin that eventually sent him back to the midwest. â€Å"Gatsby believed in the green light, the orgastic future that year by year recedes before us. It eluded us then, but that’s no matter- tomorrow we will run faster, stretch out our arms farther. . . . And then one fine morning- So we beat on, boats against the current, borne back ceaselessly into the pa st. â€Å" As the final words spoken in the novel, this paragraph brough the novel full circle to the theme of significance of the past to dreams of the future. The green light represents the future and the struggle of people to achieve their goals by changing who they are. The problem, is that the past and present tend to draw them back into their past lives. Which the characters in the story then use to try and help them create a better future for themselves. The green light is their desire to continue to keep their optism and the hope that they will never lose it when looking to their future, even if it becomes harder and harder to achieve their personal goals that would fulfill their great American dream.

7 Tactical Fixes for Syntactical Impact

7 Tactical Fixes for Syntactical Impact 7 Tactical Fixes for Syntactical Impact 7 Tactical Fixes for Syntactical Impact By Mark Nichol Writers often miss opportunities to push home a point or spotlight an interesting observation by ignoring or not attending to the effect of cadence and syntax on written communication. Such incidents are like a standup comedian placing a punch line in the middle of a joke. Here are some examples of slight adjustments of sentence construction for maximum impact: 1. â€Å"He argued that the court is hardly a legal entity, for a variety of reasons.† The point of the sentence is buried in its midsection, after which a modifier is tacked on, causing the sentence to stagger to a weak ending. Revise as follows: â€Å"He argued that the court, for a variety of reasons, is hardly a legal entity.† 2. â€Å"The Chinese were growing lettuce by the fifth century BC, where it represented good luck.† Because â€Å"the fifth century BC† could be treated grammatically as a location, the second clause could be misunderstood to refer to the time, not the place, which is furthermore only weakly implied by â€Å"the Chinese.† Strongly link the superstition to the people, rather than the country: â€Å"The Chinese, who considered lettuce a symbol of good luck, were growing it by the fifth century BC.† 3. â€Å"More than 600 schools or school districts nationwide have blocked the Web site, according to cofounder John Doe. Doe, who started the site . . .† â€Å"According to† attributions are often stronger at the head of a sentence. This revision also avoids the clumsy repetition of Doe’s name at the end of one sentence and the beginning of the next: â€Å"According to cofounder John Doe, more than 600 schools or school districts nationwide have blocked the Web site. Doe, who started the site . . .† 4. â€Å"Asquith recognized that the majority of his party wanted to steer clear of the approaching conflict- and, more to the point, a majority of his Cabinet.† Wait the majority of his party wanted to steer clear of a majority of his Cabinet? Huh? Well, that’s what it says. But that’s not what it means. Here’s what it means: â€Å"Asquith recognized that the majority of his party- and, more to the point, a majority of his Cabinet- wanted to steer clear of the approaching conflict.† So write it that way. 5. â€Å"Yo-yos were first used as deadly weapons, not as toys.† The mildly startling fact about the toy’s origins is best held back until the end of the sentence: â€Å"Yo-yos were first used not as toys, but as deadly weapons.† 6. â€Å"The model takes the social systems surrounding the alcoholic as crucial, most often the family.† The specification of the primary social system should immediately follow â€Å"the alcoholic,† the focus of the sentence, rather than being buffered and weakened by the additional phrase â€Å"as crucial†: â€Å"The model takes the social systems surrounding the alcoholic, most often the family, as crucial.† 7. â€Å"There, it’s become fashionable to hate Jews, as they are the proxies for Americans in the Middle East, some say puppets.† As the sentence is written, the last phrase seems a muttered aside, rather than a key component of the statement. Inserting it, enclosed in em dashes, in the middle of the sentence gives it the prominence it needs: â€Å"There, it’s become fashionable to hate Jews, as they are the proxies some say puppets for Americans in the Middle East.† Want to improve your English in five minutes a day? Get a subscription and start receiving our writing tips and exercises daily! Keep learning! Browse the Grammar category, check our popular posts, or choose a related post below:English Grammar 101: All You Need to KnowComma Before ButForming the Comparative of One-syllable Adjectives

Its very clear from the writings of the Spaniards in New Spain that Essay

Its very clear from the writings of the Spaniards in New Spain that the conversion of the Azetecs Christianity didn't completely - Essay Example They made statues representing their gods. Some of the gods were made from seeds and vegetables joined by blood from human hearts. Cortes reported this in his letter citing â€Å"after they are made they offer them more hearts and anointed their faces with blood† (Andrea and Overfield 463). The sacrifices involved anointing these idols with sacrificial blood. The market place formed an important part of their culture. Cortes, who led the Spanish forces that conquered the Aztecs, reported, â€Å"This city has many squares where trading is done, and markets are held continuously† (Andrea and Overfield 462) Cortes continued to expound on the expanse of the market and the range of merchandise. He indicated that he could not report all of them saying â€Å"but they are so many and so varied† (Andrea and Overfield 463). The Spaniards conquered the Aztecs in 1521, after which they introduced Christianity to the inhabitants of the fallen empire. However, despite the intr oduction of Christianity, their transformation was not complete as they continued with some of their cultural practices. Andrea and Overfield presented an excerpt from the writings of Duran. Duran served as a priest from 1556 until his death in 1588. One of the ways that the priest noted remained unchanged was attendance to the market places. The markets, as previously indicated, formed a chief part of the Aztec culture. The markets were operational throughout, and people were compelled by law to attend the market fairs. Duran observed that the custom of attending markets after a number of days continued among the people. He wrote, â€Å"The markets were so inviting, pleasurable, appealing, and gratifying to these people that great crowds attended, and still attend†¦Ã¢â‚¬  (Andrea and Overfield 405). He further noted that when the market days were on Sundays, no one attended the mass. He noted, â€Å"Occasionally, this falls on Sunday, and no one hears the mass in the area o f the town where the market is held† (Andrea and Overfield 405). This attachment to the market place was so strong that it was placed first before Christianity. Duran presented this in what he thought was the most probable reply from a woman choosing between heaven and the market. He perceived the woman would say, â€Å"Allow me to go to the market first, and then I will go to heaven† (Andrea and Overfield 405). Duran identified three ways through which a person could receive honor in Aztec. These included soldiery, religion and trade. Soldiery was the first and the main way, while trade was the least admired. Nevertheless, it presented a credible way of attaining honor. Traders who traded in expensive wares and acquired wealth received recognition like brave soldiers. Duran reported that â€Å"and so they were considered among the magnates of the land, just as the valorous soldier† (Andrea and Overfield 404). Thus, the market presented one way that was accessibl e to most of the people. Duran noted that this attachment to the market as a way to acquire status did not end with the introduction of Christianity by the Spaniards. He noted of how merchants saved up to twenty years and prepared expensive parties, which consumed all their savings. Duran added, â€Å"This could not be wrong except that for their celebration they await the day on which the god was honored† (Andrea and Overfield 405). This indicated the unchanged connection between trade and honor in the people’s life. Additionally, attending markets presented a form of

Nursing Ethics and Leadership Assignment Essay Example | Topics and Well Written Essays - 500 words

Nursing Ethics and Leadership Assignment - Essay Example They also carry embody the vision, mission and values of the unit and share with their staff. In line with the budget, we are also charged with managing human resource, ensuring patient and staff satisfaction, maintaining a safe environment for staff, patients and visitors, ensuring standards and quality of care are also maintained. Nurse Managers are also responsible for hiring, training and developing employees. That must however be done through a very economical way. It is common knowledge that all facilities are faced with the problem of scarce resources which must meet all the patients need. Nurses are supposed to be empathetic and work according to the Science of Safety principles of safety design. Therefore, as a nurse manager, it is my responsibility to ensure that every patient’s individual needs are met in an empathetic but professional way. For example, a patient may require a special room. This will be done as per the institution values and protocols. Another protocol is involving the patient and family centered care. As such, as a nurse manager, I am tasked with ensuring that their customers get thee best care possible. By having a supportive and very caring environment where the patients are allowed interactions with their patients, this can be a reality (Studer, 2003). They are also tasked with ensuring quality food, translation or sign language services for their customers. Therefore, our operational costs must be all inclusive. It is important to note that as a nurse manager, I am supposed to subscribe to the Joint Commission for Medicare & Medicaid Services. The local government too has a stake in the quality of care delivered by the facilities to the general. It is therefore by default that a nurse manager draw a budget that is compliant with all these protocols lay down. The nursing codes in western countries specify that a nurse’s primary responsibility is to the patient and not the doctors or employees. One of

The Vikings Assignment Example | Topics and Well Written Essays - 250 words

The Vikings - Assignment Example historians reached Polynesia in the 16th century, the ability of Polynesians to carry out distant voyages had already been lost and they had been widely isolated on scattered islands. This, coupled with the lack of literate persons to record their history, led to little being known about their culture and expansion (Hadley 19). This led to the eventual decline of both groups. The main reasons for exploration were trade and colonization. The case is the same with the Vikings, but, a bit more is known about their expansion since they are said to have explored places such as North Africa, North Atlantic, Middle East, and Russia, mostly raiding, pillaging and engaging in trade. Vikings built very sophisticated ships for various uses, mainly raiding and trading, and their ship craftsmanship was superb. The Polynesians mostly relied on outrigger canoe construction techniques to build their vessels and had navigators at various islands. Trade was more developed among the Vikings compared to the Polynesians (Hadley 33). Both cultures were non-literate and had no literary

Griffith's theory of fracture Coursework Example | Topics and Well Written Essays - 1000 words

Griffith's theory of fracture - Coursework Example Ceramics and Metals have different atomic structure and ionic bonding. Ceramic materials have both ionic and covalent bonds. Ionic bond is the one that keeps them brittle. Ionic bond is lose and no definite direction.The positive and negative ions are arranged and are held together by attraction created by each other of different charge. When stress is applied, ions slide past each other then goes to different directions; ions of the same charge bumps and trying to repel each other; causing the atoms to spread. The material then breaks. In metals, the atomic structure consist more positively charged ions on a flow of negatively charge electrons. The electrons allows the positive charge ions to slide and roll past each other without breaking the bond when a certain stress is applied. This causes the metal to be tough. 2) Glass in general has a low tensile strength. This lies entirely with the fact that glass is a solid lacking crystalline structure or namely amorphous solid. Amorphous solid has a moving structure of molecules and are not compact, this results to having a low tensile strength than of other solids. However, there are methods of somehow improving glass’s tensile strength, strengthening them. One is by soaking the glass into a bath of potassium nitrate solution on an about 400 to 450 degrees Celsius having. Potassium nitrate has larger molecule structure than of a common sodium nitrate molecule in the surface of the glass. The process will now replace the sodium nitrate on a glass by the potassium nitrate in the bath solution, leaving the glass having a thick layer and a hard wedge. This is called â€Å"chemical strengthening†. Another one is called â€Å"heat strengthening† where a glass surface is heated for about 1100-1500 degrees Fahrenheit then suddenly cooled. After suddenly cooling, the glass molecules compresses, thus having a thick and compressed layer than before. 3) Griffith’s equation steps directly not to the strength of a material but the fracture in it and how hard can it withstand a force before it collapses. Fracture is the propagation of a crack or a flaw across loaded or force-applied segment. Toughness is the property of a material to withstand fracture. Now glass has literally low resistance to fracture than steel has. In Griffith’s equation, you would get stress over strain or Young’s modulus of a material first then that you will determine its toughness. A glass generally has only 50-90 GPa. Its ability to resist fracture is very low compared of steel which has a stress over strain ratio of around 190 to 210 GPa. This makes steel as a more preferable material than glass. 4) Elastic deformation by definition is reversible. Meaning, the material will return to its original state when stressed and bending stress is no longer applied. Uniform plastic deformation is an irreversible deformation where the material strains uniformly upon stress. The material will not ret urn to its original state rather it cracks or ruptures when certain stress is strong enough for the material to withstand. Local plastic deformation or also known as â€Å"necking† differs from uniform plastic deformation by means of the strain applied. It is a mode of tensile deformation where relatively large amounts of strain localize disproportionately in a small region of the material. The localised portion of the material where there is a decrease in local area became the basis for â€Å"neck†. 5) In rubber elasticity the polymer chains of an elastomer coils at random at a relaxed state. On extension, the chains are stretched out, and their conformational entropy is reduced. This is the reason why a rubber material, when suddenly relaxed from extension, snaps back. This is the basis in an elasticity modulus of a material. The material is highly elastic when its stiffness and extension are balanced together. Stiffness is an extensive property of a material to resi st deformation. The high the stiffness can be the high the material’s extensions. 6) Thermosetting resin has a composition

Kudler Fine Foods Essay Example | Topics and Well Written Essays - 500 words

Kudler Fine Foods - Essay Example Although Kathy’s store concept is great and she has no direct competition- her overwhelming responsibilities are hindering her efforts as the general manager of her store. In order for Kudler Fine Foods to expand into new geographical areas, Kathy Kudler must redefine her organization and utilize effective time management to increase her personal time efficiency as well as her staffs. In order for the Kudler store to expand and allow for great overall efficiency and time management a number of factors must be corrected. Right now Kathy is in charge of all ordering and product control, this will be cumbersome as the product line increases along with consumer demand. Kathy must develop a centralized management and control of the products, assortments, and pricing. Secondly, she must delegate the task of supply management to one manager to include product buys and invoice matching. There are several software companies such as Aldata that offer a complete software interface to int egrate the inventory controls. (www.aldata-solution.com) Thirdly, Kathy must optimize inventory levels by utilizing demand forecasting, and take account of the products expiry dates and ensure that her perishable items are being purchased instead of wasted away.

Griffith's theory of fracture Coursework Example | Topics and Well Written Essays - 1000 words

Griffith's theory of fracture - Coursework Example Ceramics and Metals have different atomic structure and ionic bonding. Ceramic materials have both ionic and covalent bonds. Ionic bond is the one that keeps them brittle. Ionic bond is lose and no definite direction.The positive and negative ions are arranged and are held together by attraction created by each other of different charge. When stress is applied, ions slide past each other then goes to different directions; ions of the same charge bumps and trying to repel each other; causing the atoms to spread. The material then breaks. In metals, the atomic structure consist more positively charged ions on a flow of negatively charge electrons. The electrons allows the positive charge ions to slide and roll past each other without breaking the bond when a certain stress is applied. This causes the metal to be tough. 2) Glass in general has a low tensile strength. This lies entirely with the fact that glass is a solid lacking crystalline structure or namely amorphous solid. Amorphous solid has a moving structure of molecules and are not compact, this results to having a low tensile strength than of other solids. However, there are methods of somehow improving glass’s tensile strength, strengthening them. One is by soaking the glass into a bath of potassium nitrate solution on an about 400 to 450 degrees Celsius having. Potassium nitrate has larger molecule structure than of a common sodium nitrate molecule in the surface of the glass. The process will now replace the sodium nitrate on a glass by the potassium nitrate in the bath solution, leaving the glass having a thick layer and a hard wedge. This is called â€Å"chemical strengthening†. Another one is called â€Å"heat strengthening† where a glass surface is heated for about 1100-1500 degrees Fahrenheit then suddenly cooled. After suddenly cooling, the glass molecules compresses, thus having a thick and compressed layer than before. 3) Griffith’s equation steps directly not to the strength of a material but the fracture in it and how hard can it withstand a force before it collapses. Fracture is the propagation of a crack or a flaw across loaded or force-applied segment. Toughness is the property of a material to withstand fracture. Now glass has literally low resistance to fracture than steel has. In Griffith’s equation, you would get stress over strain or Young’s modulus of a material first then that you will determine its toughness. A glass generally has only 50-90 GPa. Its ability to resist fracture is very low compared of steel which has a stress over strain ratio of around 190 to 210 GPa. This makes steel as a more preferable material than glass. 4) Elastic deformation by definition is reversible. Meaning, the material will return to its original state when stressed and bending stress is no longer applied. Uniform plastic deformation is an irreversible deformation where the material strains uniformly upon stress. The material will not ret urn to its original state rather it cracks or ruptures when certain stress is strong enough for the material to withstand. Local plastic deformation or also known as â€Å"necking† differs from uniform plastic deformation by means of the strain applied. It is a mode of tensile deformation where relatively large amounts of strain localize disproportionately in a small region of the material. The localised portion of the material where there is a decrease in local area became the basis for â€Å"neck†. 5) In rubber elasticity the polymer chains of an elastomer coils at random at a relaxed state. On extension, the chains are stretched out, and their conformational entropy is reduced. This is the reason why a rubber material, when suddenly relaxed from extension, snaps back. This is the basis in an elasticity modulus of a material. The material is highly elastic when its stiffness and extension are balanced together. Stiffness is an extensive property of a material to resi st deformation. The high the stiffness can be the high the material’s extensions. 6) Thermosetting resin has a composition

Incident Command System; Principles and Features Part I; Mitigation Case Study

Incident Command System; Principles and Features Part I; Mitigation and Risk Reduction - Case Study Example This information will all be acquired at the city council’s office or the city building authority The other important aspect of this floor plan is to get information about the infrastructure, drainages and gutters, general slope of the land, any nearby streams and rivers, underground pipes and cables and other features that are in the area. It also helps in determining the accessibility of the whole area, type of terrain, location of the safe houses and whether they can easily be accessed â€Å"The rapid needs assessment is a description of the extent of the damage that is sustained by the community. It is the general scope of the disaster in the area† (Flood plain management, 2011). This information can be acquired in the local authorities or any disaster management officials in the city, such as the Red Cross. The rapid needs assessment contains information on: Medical needs and availability of resources – This is information on the injuries, loss of lives and the number of victims that required assistance. It also states the number of medical teams that were at the scene of rescue and the facilities that are functional in the area. The availability of adequate medical equipment and supplies and the requirement for outside assistance are also documented in this assessment. Mass care – This is the mass equipment such as shelter, food and water and relief supplies that are available for the rescued group and the community in general once they are moved from the affected areas. Effect on infrastructure – This is the assessment of the amount of damage caused to the infrastructure. This is the impact on things such as buildings, roads, sewages and drainages, power generating facilities, schools and hospitals, communication lines, water pipes and distribution facilities. Release of dangerous materials – These are the materials that may have been released and can cause harm to the

Final Project 1960 Time Capsule Essay Example for Free

Final Project 1960 Time Capsule Essay After receiving a very intriguing call from my colleagues, about a great time capsule find, I made my immediate departure for a little place we call the Red Zone previously known as Colorado. As I arrive I help my colleagues to unearth a time capsule from the period of the 1960s. We carefully opened the capsule that had intrigued us all so much to find five articles inside that told a great story of our past and of the decade beginning in 1960. The following is a summary of my findings within the capsule. The first of the five articles contained within the capsule was The Berlin Wall of 1961, also known as â€Å"The Iron Curtain†. This wall once more than 30 miles of barbed wire was a barrier between the Communist East Germany and the Democratic West Germany, became a series of concrete walls up to fifteen feet high, 96 miles long and guarded by towers armed with guards. After WWII Germany was split into four zones, three controlled by France, Britain, and The United States, and the other one by The Soviet Union; the Berlin Wall was constructed to separate the zone (East Germany) that was controlled by the Soviet Union from the zones (West Germany) controlled by France, Britain and the United States. It was here at the Berlin Wall that John F. Kennedy gave one of his memorable speeches, â€Å"There are many people in the world who really dont understand, or say they dont, what is the great issue between the free world and the Communist world. Let them come to Berlin. There are some who say that communism is the wave of the future. Let them come to Berlin. And there are some who say in Europe and elsewhere we can work with the Communists. Let them come to Berlin. And there are even a few who say that it is true that communism is an evil system, but it permits us to make economic progress. Lasssie nach Berlin kommen. Let them come to Berlin.† The construction and demolition of the Berlin Wall(1989-90) are important milestones of the Cold War. The second item found in the capsule was the March on Washington of 1963. Attended by some 250,000 people, it was the largest demonstration ever seen in the nation’s capital, and one of the first to have extensive television coverage (Ross, 2007). The stated demands of the march were the passage of meaningful civil rights legislation; the elimination of racial segregation in public schools; protection for demonstrators against police brutality; a major public-works program to provide jobs; the passage of a law prohibiting racial discrimination in public and private hiring; a $2 an hour minimum wage; and self-government for the District of Columbia, which had a black majority (Ross,2007). Demanding jobs and freedom from the nation’s capital this march successfully pressured the Kennedy administration to initiate a civil rights bill in Congress. This is also when Martin Luther King gave his â€Å"I Have a Dream† speech. Although it wasn’t until the Civil Rights Act of 1964 that the demands of the march were met, it was a major point in the peaceful war for civil and equal rights for all Americans. Without this peaceful demonstration the civil rights movement could have been pushed even further back in its effort for an equal nation. The effects of this event can still be seen today as we are now seen as American rather than white and black or rich or poor. The third item discovered in the capsule was the assassination of President John F. Kennedy on November 22, 1963. On this day President Kennedy accompanied by his wife, John Connelly and his wife Nellie rode in a motorcade through the streets of Dallas, TX. It was during this ride that President Kennedy was shot around 12:30 pm the driver then rushed the President to Memorial Hospital where he was pronounced dead at 1:00pm. This horrible travesty shook America for years to come. News of the assassination changed the source of news from then on. Until this point newspapers had been the main source of news, until the assassination which brought on the longest uninterrupted television broadcast to date. The assassination also stuck fear in the African-Americans that the assassination would put a halt to the progress for civil rights. However, the assassination seemed to spur the civil rights movement which resulted in the Civil Rights Act of 1964 signed by President Lyndon Johnson. The assassination also changed the way the secret service operates today. Although during those times the President  was freer to move around openly, now secret service agents keep the president more secure and his availability limited. It is also thought that had the president not been assassinated the Vietnam War would have ended and many of our troops would not have died. The assassination opens up the possibility of â€Å"what if?†, and fueled conspiracy theorist for many, many years to come. This showed the weakness of American by its own hand. The fourth item in the capsule was the moon landing in 1969. July 16, 9:32am three astronauts (Neil Armstong, Buzz Aldridge, and Michael Collins) sit waiting for launch permission. By 9:44am they are in Earth orbit, July 20 at 10:56pm Neil Armstrong takes his first step on the moon. With more than half a billion people watching on television, he climbs down the ladder and proclaims: Thats one small step for a man, one giant leap for mankind. (htt5). This was proof of great technological advancement and completion of the challenge set forth by President Kennedy over nine years ago. Project Apollo took on a life of its own over the years and left an important legacy to both the nation and the proponents of space exploration. Its success was enormously significant, coming at a time when American society was in crisis (htt6). This event showed the world and Americans everywhere that The United States was still the ultimate power by demonstrating to the world what the United States could achieve. The moon landing changed the way we viewed the Earth as they pointed a small portable camera toward Earth, showing just how small and fragile the planet really is in the scheme of the universe. The samples taken and brought back from the moon landing opened up knew scientific testing and led the way to multiple other moon landings and advancing our knowledge of space itself. The last item in the intriguing capsule was the Woodstock Music Festival of 1969. This was a three day concert at Max Yasgur’s dairy farm in the town of Bethel. More than half a million people came together united in a message of peace, openness and cultural expression – and demonstrated how a generation could be heard (htt7) Woodstock is committed to living by its principles – we believe in universal human rights, ethical business practices, unfettered creative expression, free trade, the loving care of our planet, the power of the individual to make a difference, and the  overwhelming impact of communities to act as agents of peaceful change (htt7). However, the festival involved music (rock ‘n roll), drugs, sex and nudity. This festival came at a time when American had been through hard times. With the Civil Rights Movement, the Vietnam War, and the assassination of Martin Luther King the United States was tired and weary. The peaceful concert changed the way music was marketed from then on, now knowing that fans were willing to give up popular amenities to have sight of the musicians they loved. The change on music and pop culture of the time was historic. In 1969, rock critic Ellen Sander appraised the immediate impact of the Festival this way: No longer can the magical multicolored phenomenon of pop culture be overlooked or underrated. It’s happening everywhere, but now it has happened in one place at one time so hugely that it was indeed historic . The audience was a much bigger story than the groups. It was major entertainment news that the line-up of talent was of such magnificence and magnitude (thirty-one acts, nineteen of which were colossal) . These were, however, the least significant events of what happened over the Woodstock weekend. What happened was that the largest number of people ever assembled for any event other than a war lived together, intimately and meaningfully and with such natural good cheer that they turned on not only everyone surrounding them but the mass media, and, by extension, millions of others, young and old, particularly many elements hostile to the manifestations and ignorant of the substance of pop culture. (htt8). This change in pop culture has left an undying footprint on the history of the world with its new found music, art and literary styles. It is clear after examining and researching the incredible articles within the time capsule that the 1960 era was an extreme time of change for the American people. This decade in our history so full of such life changing events not only in the United States but also in other countries that rely on support from the United States. Its story shows our ability to adapt to ever changing situations around us and the resilience of the American people. Whether it is fighting Communism, the loss of a great leader, fighting for our rights, landing on the moon, or expressing or freedom in culture we are a strong nation and when faced with a great challenge we answer that challenge with a great success. Although many have been lost  along the way as a whole we stand one nation, united. References (n.d.). Retrieved from http://www.tenfactsabout.co.uk/0003berlinwall.htm (n.d.). Retrieved from http://mlk-kpp01.stanford.edu/index.php/encyclopedia/encyclopedia/enc_march_on_washington_for_jobs_and_freedom/ (n.d.). Retrieved from Civil Rights March on Washington (History, Facts, Martin Luther King Jr.) | Infoplease.com. Infoplease. (n.d.). Retrieved from http://www.theguardian.com/world/2013/nov/19/john-f-kennedy-assassination-racial-equality-jfk (n.d.). Retrieved from http://www.nasa.gov/mission_pages/apollo/apollo11_40th.html (n.d.). Retrieved from http://history.nasa.gov/ap11-35ann/legacy.html (n.d.). Retrieved from http://www.woodstock.com/ (n.d.). Retrieved from http://www.woodstockpreservation.org/SignificanceStatement.htm http://www.u-s-history.com/pages/h1867.html. (n.d.).

Demand and Supply of Gold in India

Demand and Supply of Gold in India Demand is the relationship between price and quantity demanded for a particular goods and services in a particular circumstances . For each price the demand relationship tells the quantity the buyers wants to buy at that corresponding price . The quantity the buyer wants to buy at a particular price is called the Quantity Demanded. supply is the directly proportion of price when the price of the commodity is increased then the supply of that product also increase or visa- versa. ON THE BASIS OF GOLD COMMODITY:- In the relation of gold the demand cannot affected or doesnt matter of price, demand and supply because it is luxurious product and they always usable for functions and many of areas. The price of gold is increases demand then the demand and supply also occur in positive range. The term can be movable as follows:- When the price is increases then the demand and supply can movable in upward direction. When the price is decrease then then the demand and supply can change because the demand is high and supply will be decreases in range. The main concept is started from here to analyze the demand and supply of gold in India. The price is the main factors which can be changing whole style of product sale in the market but gold is a luxurious product and the price does not matter there they r directly based on the willingness to buy the products. This is analyze on the basis of previous data when the price is 17000 rs. In india and what about the demand and supply of the gold in market this will shown as follows:- It schedule is rougly showing to how the relation between price , demand and supply that will be arises on same direction this is only for gold product not for other . It is the concept demand curve is always downward slope and the supply curve move on upward . it means when the price of commodity is increase then demand is decrease and the supply is also increases but in that condition the demand and supply moved in same proportion . THE MAIN OBJECTIVE OF GOLD DEMAND AND SUPPLY ARE AS FOLLOWS:- When the price is automatically increased in year 2005 then the consumers are simultaneously struggling. In present time the market price of gold is 19,171 Rs. Per 10 gram , after hitting a record high of 19,257 rs. Earlier in next week. In the time of festiwal the price is increase then the consumer is struggling to buy but in small range capacity. Basically in the seassion of dhanteras , diwali the demand of gold is high and the consumer can buy without any price problem. BRIEF DISCRIPTION ABOUT HIGH PRICE CUT DEMAND:- This condition doesent seen in the gold market because when gold was a barbarious relic the gold price stood at just 12000 rs. In that condition the various changes are coming in the gold and silver market according to as follows:- A CHANGE IN THE NATURE OF THE GOLD INVESTORS JEWELRY At the turn of the century , the jwelery and industrial gold buyers , alongside rural , agicultural Indian demand, dominated the gold price. In a developed country the gold was not bought for itself and its importance. That condition the major role basically in jwelery, often the cheaper part of piece of jwelery. in that time the prices cannot rises in that much, in that condition the gold price is high .it means when the price of gold is high then the buyers are low. The buyers are still there, but they want in small volume or range due to high price of that commodity. In that condition the market are focuses in middle class person to increase the capability power and creat high growth INDIAN DEMAND When they targeted to middle class family to increase the demand in that level of customer mind to focuses in that level of customer. The market wants to increase the efficiency and they also aware that gold is traditionally valuable in india and they aeare that customer can easily brought due to the need and knows the condition of market. After that marketers can expect that the price of gold is higher then doesnt affect in that market strategy because it is the investment terms which is basically effort by Indian customers. They always analyse that when the price is high then it affect in supply terms. WESTERN JEWELRY , COIN AND BAR DEMAND According to the analyser to analyse that in tradition the gold market cheap jewelry basically invested in to coins and small bars is and they analyse to investing in that areas of Indian market.the Demand ofr gold is always protect the wealth andprotect the mony market loss to maintain and equal balance generated. The marketers also seen the quantity and quality of demand dropped initially, as jewellery demand always decline or down faced in the market but is now gathering pace and actually increasing on both fronts, especially if the marketer add the small coin and bar demand to it then the gold moves up the ladder of exclusively and expensive decorative items again higher quality gold jwelery demand (accepting high prices) is growing again. At the last the marketer seen that the demand of jwelery is always increases. And generated high efficiency in the market. 2. A WIDENING IN THE NUMBER AND SIZE OF GOLD INVESTORS GOLD EXCHANGE TRADED FUNDS The size of the market is high and large number of investors in the market and always want to increase the return in future trend. In the modern changes the market price of gold is always high but no effect in the consumption power they always choosen gold and buy for future trend because it always slope in downward. There are so many factors which changes the consumption and buying power of customers the main factors are as follows like income and price . the price of gold is simultaneously increases but demand is also movable in same directions. CENTRAL BANK The story of central banks and gold is a sad one. As both politicians strove to establish a doctrine that paper currencies, with no gold backing, better serve as money then gold does. By persuading people that central bankers were capable of being a satisfactory and the gold was a barbarous relic that had no place as money, they sanctioned dual policy of selling and sidelining gold as mony and accelerating the supply of gold to the point that the easy gold picking were exhausted . now central banks have had to revert to their underlying belief that gold is a vital reserve assts , particlurly when drems fade and realities take over . Higher price in their case have led to a cessation of sales and subsidential buying. SWITCHING FROM OTHER MARKETS TO THE GOLD MARKET As a gold and silver prices rise just like a thermometer measuring global financial uncertainity and instability , more and more investors are ntering these markets for the first time, not for profit . , but for protection against such fears and in an attempt to preserve the wealth they have. These investors come from the entire spectrum of investors across the length and breath of our world. This is the quintessential reason why demand for gold will rise as gold price rise. WHY ECONOMISTS USE ELASTICITY Elasticity means degree of level changes in the particular commodities is called elasticity But here, we are discussed about changes in the demand and supply of gold in demand and what are the various tools to find out the degree of demand of gold in india. THE BASIC USE OF ELASTICITY IN ECONOMISTS AS FOLLOWS:- Economist wants to compare gold demand all the times. Is gold demand more price sensitivity then silver demand . Is the supply of gold is equal. An elasticity is a unit- free measure. By comparing market using elasticity it does not matter how we measure the price or quantity in the Indian market. Elasticities allows to identify the differences among markets without standedizing the units of measurement. THE ELASTICITY OF DEMAND MEASURE BY AS FOLLOWS:- PRICE ELASTICITY OF DEMAND INCOME ELASTICITY OF DEMAND CROSS ELASTICITY OF DEMAND PRICE ELASTICITY OF DEMAND Degree of level changes by the price of commodity . the gold commodity is directly not affected in the demand because it is a luxurious goods. According to the gold the descriptions are as follows Gold price have been rising this year and this is the news that dominates in newspapers . The last time gold prices rise at such pace was in 1980. In fact gold price never touched the hights they had reached in 1980 and in fact were at their lowest in he year 1999. The first point is to be noted is that both gold and oil prices move in together . both were at their highest in 1980 and while oil has become far more expensive that it ever was , gold prices still not a very high compare to where they were in 1980. The prices are taking in high price adjusted for inflation and not the nominal prices that we see going up year after year. SECOND POINT to note is that gold prices elasticity is negative . Higher the price of gold, higher is the demand for gold. This is a unique feature of gold , as many other commodity whose prices go up sees lowering of demand . When prices rise the most that the demand is the highest, pushing up prices further. In the year 2007 , gold prices went up by nearly 20 % compared to price in 2006 . Demand for gold went up by nearly 5 % . when people say prices goes up , they normally tend to consume less of the good, including essential items like oil and petrol. The nominal price always stay above the previous price, therefore gold is never seen as a risky investment compare to real estate, the share market and the money market. Gold is a unique metal . it has been the most attractive metal for thousands of year. The roman empire and the Egyptian civilization were known to have used gold more then 2000 years ago. India is a growing primarly country because of income growth in the country leading to higher purchases of jwelery . When the recession subsides and the industry looks up and real estates prices rise again gold price should come down from the heights they occupy today. SO GOLD IS SAFE INVESTMENT ? THE ANSWER IS CLEARLY YES. AS gold prices do not come down in nominal terms . however as the economy improves and other forms of investment become attractive , the return on gold come down drastically and may sometimes in real terms become negative . however jewellery has a sentimental value attached to it too, therefore even when price come down , people remain proud of their gold purchases . Buying gold makes sense during the time the rest of the economy is receding, but when economic growth and industrial growth is handsome . like in india now, investing in gold might deliver the lowest returns that one could have obtained . however , this return is in all likelihood is risk free, therefore it makes sense for those who like to avoid risk . it is important to remember that usually higher the risk , higher is the rate of return for any investment. At last it is simply explain that the price of the commodity is increase then the gold is not affected because it is type of investments in the market and always given positive return . so it is future profit generated investments which is always given better and high return to the customers. THE MAIN ADVANTAGES OF THE GOLD AND NOT AFFECTED PRICE AS FOLLOWS:- THEY ALWAYS GIVEN POSITVE RETURN TO THE BUYERS IT IS THE INVESTMENT FOR FUTURE BENEFITS THEY ALWAYS GIVEN POSITIVE GROWTH PRICE IN THE MARKETS. THE PRICE CAN NOT AFFECT TO BUY THAT PRODUCT. INCOME ELASTICITY OF DEMAND As a persons income rises , he or she can buy more goods at a given price at any particular time . but the ability to buy more goods does not necessarily imply the willingness to do so . It means when then the consumers income is rises or dicreases then directly affected to consumption capacity. If the demand of the goods rises as income rises, then that good called a normal goods . Also the demand for the normal goods falls as income falls . the demand for a normal goods and incomes are directly related. The demand for a inferior goods income rises and good falls . the demand for an inferior goods and income are inversely affected. SOME IMPORTANT ASSPECTS WHICH AFFECT INCOME ELASTICITY OF DEMAND AS FOLLOWS:- PREFRENCES:- Peoples preferences affect the amount of good they are willing to buy at a particular price. A change in favour of goods shift the demand curve rightward. But in the gold commodity the income is doesent affected because the always show when the consumers income is rises thend the demand is also increases and visa versa because it is a investments which wa BENEFITTED FOR FUTURE. NUMBERS OF BUYERS:- The demand for a goods in a particular market is related to the number of buyers in the area . The more buyers, the higher demand , while the fewer buyers , the lower the demand . EXPECTATION OF FUTURE PRICE:- Buyers who expect the price of the goods to be higher next month may buy the good now thus increasing the current demand for that particular goods. Buyers who expect the price of the good to be lower next month may wait until next month. POPULATION :- Large no. Of buyers are in Indian market the customers and population are so high in Indian market . Examples:- india have created so much demanded for goods and services because of its massive population. ADVERTISING:- An increase in a firms effective advertising will be cause in demand for the product being advertise. For examples :- Indian have been buying gold for the last few years . however, there is no another addition cost are included in that luxurious good. CROSS ELASTICITY OF DEMAND It means when the price of the substitute commodity is increase then the other product is dicreases and visa versa . there is two commodities in iindia is silwer and gold . When the price of the silver is dicreases then the silver commodity is increases and gold price is dicreases then the demand of that commodity is increases. Now the bullion banker is net short gold when he conduct this operations . remember he borrowed gold and now he has a financial assets . he is making 5 % return on the spread , but he now has a gold price risk . as a banker he is not normally business of putting on speculative positions . so basically, in doing this operation but bullion bankers has a hedged the gold price and he takes a small margin- like a half of %- from this intermediation . in doing so , he allows private market participants to go short gold . thats why we elide the two phrases- going short in the gold market and gold borrowing . the ultimate borrowers in the gold leading operation are these shorts in the gold future and forward markets . Now we have a conservative set of gold leading number and we have a more aggressive set of such numbers . our range of estimates emplies that somewhere between 10000 and 16000 tonnes of the official sector gold position has left thse results way of leading the process . TABLE 1 : WHY OFFICIAL SUPPLY/DEMAND EXCEEDS MAJORITY OPINION ESTIMATES AN ARGUMENT FROM THE SUPPLY SIDE Total Gold Loans Outstanding  Ãƒâ€šÃ‚  Ãƒâ€šÃ‚      BOE GFMS December 1993 4,750 1,600 June 1995 9,250 2,200 Note: All Quantities in Tonnes  Ãƒâ€šÃ‚  Ãƒâ€šÃ‚   This discrepancy was so large that tried to be conservative and for no good reason, chopped the 9000 tonnes down to 6000 tonnes because that 6000 tonnes figures was already so far removed from the official numbers . in any case , this bank survey implied big , big errors in the consensus supply/demand balances and half of a lot more gold lending than anyone thought . Now look , gold lending began in earnest in the early 1980. By 1995 it was a process that had been going on for more than ten years . now, what if there were 6000 tonnes of gold loans not 2000 tonnes of gold loans as implied by the consensus supply/demand statistics . that mean that there had been 4000 tonnes more lending , most of it over the last ten year period . gold lending was a small activity during the 1980 . it was a much bigger activity during the 1990, so obviously it was a business that was occurring on an increasing scale . if the discrepancy was 4000 tonnes over 10 to 15 years , 300 to 400 tonnes a year well , then it was probably 200 tonnes a year in the 1980 and it was probably nearer 600 tonnes a year by 1995. That mean supply and demand were underestimated by something like 600 tonnes a year . If we total these three demand items we arrive at the following:- Table 2 Metric Tonnes    1999 WGC gold demand for jewelry, bar and coin in 27 countries 3,282       GFMS gold jewelry demand in an additional 7 countries 1) 268       GFMS global demand in all other uses (excluding jewelry, bar and coin) 458       Incomplete Global Demand Subtotal 4,008 GFMS Global gold demand 3,9852) GFMS occasionally report and use demand . there survey for 1998 including the estimate used here . there was no comparable estimate in their 1999 report . the WGC reported a large increase in global gold demand in 1999. Base on wgc glbal demand for trend this number is probably conservation . GFMS total gold demand exceeds this total by 170 tonnes . they attributes demand to investigate in india . From the above it is clear that the WGC survey plus select additional item from the GFMS points to a total that exceeds GFMS estimation of global gold demand . this subtotal still excludes jwelery demand in more than 100 countries. It also excludes official coin and bar demand in these 100 or more countries as well as seven additional countries mentioned above. It is basically helps to understand the total demand and supply of gold in india and they are basically helpfull for searc what r the condition can not decrease the demand and supply of gold in the market. It always search and analyse the terms and conditions which help to easily find out survey of gold in india or many countries. ANALYSIS OF DEMAND AND SUPPLY OF GOLD IN INDIA The ever increase of demand and supply of gold in india , various hypothesis have been put forward from time to time:- Demand for gold has an autonomous character. Supply follows demand. Demand exhidits income elasticity , particlurly in the rural and semi- urban areas. Price differential cretes import demand , particlurly illegal import prior to the commencement of liberalisation in 1990. A part of the demand is caused by the need to stash away uncounted wealth and income. Gold trades figures since the onset of liberalisation in 1990 shows that while the price differential narrowed from a high of around 53.1 % in 1991 to about 5-10 % currently the import volumes rise unabated. Gold demand in india increased by an annual compound rate of around 15 % from 1990 to 1998 during the period of liberalisation with growth slowing thereafter. This was high , not only visa- versa the world demand growth rate of 3.05 % but also in relation to the trend Indian . GDP growth rate is 5.5 % and Growth rate demand for oil is 3.8 % Energy and sugar is 6 and 5 % Gold imported officially for domestic use is now channelled almost exclusive via the official agents or the authorisd commercial banks. Some aspects which helps to anlyze the gold demand and supply in india.:- FUTURE TRENDS :- What is likely demand trnd for the future? Given the fact that gold demand is income-elastic, it would be safe to assume that demand will increase over the next decades. Since gifting jwelery at the time of marriage constitute the major components of demand, ball-park estimated could be on the basis of the no. Of marriage that takes place actually. On the basis of assumption around 8 million marriage r held in india per year. Gold is required for marriage by families of different income groups. GOLD MARKET IN INDIA:- The gold market in india is predominantly a market for buying and selling physical gold. In the whole sale segment, nominated agencies are the bulk importers. This market is resonabily efficient from the point of view of distribution of bars and scraps over the length of the country which takes place in a very efficient manner. Price manner is also generally observe in areas with identifical of duties and taxes. Gold leasing volume are small in comparision of physical buying and selling. Most of leasing activities taken by nominated banks on a back to back basis via supply from overseas. The market needs to develop for at leat two reasons:- To provide working capital at low cost together with gold price leading,not only to the exporter but also to jwelery manufacture for the domestic market. The existence of gold leading market is pre-condition for arbitrage free pricing of gold forward in the local market. ISSUE FOR THE FUTURE :- It would only be logical to assume that the neeed for a review of the overall policy stance with regards to gold is now being increasingly felt in official circles. As with other areas of liberalisation , the direction of change will certainly be positive, although it would be difficult to imagine any specific time frame. However the following issue are like to be the focus of policy.:- Strengthening of the infrastructures and market in physical gold. More assaying, refining and recycling capacities of international standard and accreditation are expected. Better protection for consumers, by way of the spread of hallmarking of jawelery. The emphesis will continue to be on more self regulation by jewellery manufacturing and retailers. Further liberalisation the gold import is live issue. Removal of all the remaining restriction on gold imports has been advocated by many of following groups:- Trade liberalisation for gold is a pre requisite for financial liberalisation. There is no specific advantage in restricting gold imports to the select no. Of nominated agencies. If gold is imported farely under full fiscal benefits will accure to more deregulation of gold in india. Going by Turkish example, free imports under OGL and free export are pre condition for establishing a foothold in the world jawelery market . REGULATION IN PHYSICAL AND FINANCIAL MARKETS IN GOLD IS ANOTHER MAJOR ISSUE:- Regulation in general means formulation of norms by the regulatory for : a. Risk assessment and control the regulated institution. B. Investors protections. 5. BRINGING THE GOLD HELD BY THE PRIVATE SECTOR IN TO THE ECONOMIC MAINSTREAM HAS RIGHTLY BEEN AN OBJECTIVE THROUGHOUT:- Mobilization of gold by the gout. In the past did not yield any major long term benefit. Any government led mobolization has inherent disadvantages. A better alternative would be allow holders of gold to raise capital from the banking system by way of pledge. It would be inconsistent with the spirit of liberalization to discriminate against those who saved in gold in past. A machenism can be evolved where by banks leading in deregulation of gold in india. 6. IT DEVELOPED OF E- MAONEY :- It is possible that a private sector units of account that is linked to gold may come in to existence in india, given the fact of huge private sector gold stocks. It would be advantages to look in to this possible. 7. GOLD HAVE ANY OFFICIAL MONETERY ROLE LEFT IN INDIA:- Golds role in currency issue was braught to a level of insignificance in india. There is good evidence to support the view that gold is held as an inflation hadged in india. BRIEF DISCRIPTION ABOUT ANALYSIS OF DEMAND AND SUPPLY OF GOLD IN INDIA Demand for gold is likely to contain information regarding inflation expectations. Since monitory policy is reflected in the growth of money stock and ultimately the rate of inflation, there is a case for including gold in the monetory calculus. It need to analyse the advantages in including gold held by the private sector in the broad measure for liquidity, even though gold is not anybodys liabilities. Also gold could be included in the index for the real effective exchange rate for rupees. They also indicate that :- Other thing be equal. Gold import demand has real effective exchange rate of the rupees. This is the analyse function where we analyse how to demand and supply of gold commodity can run in the market and whoch factors affect to ush the demand and supply of gold in equal range. This is the chart which are showing consumption n different year and we aware that the consumption of gold in india and where they affect. supply and demand table CONCLUSION In that demand and supply of gold in india we analyse and learn that official sellin will fill the boots ot trend following speculation in the gold market and the gold price will fall back towards its prior trading range. The global recession and strong dollar which curb gold , jewellery and bar demand have been facilitating the ability of the official sector to keep the gold price low. The forces for higher gold price will build. Though it may not happen over the short run in the long run the dollar will fall- and substantially in our view. A dollar decline will lower than the price of gold in countries outside, which will in turn stimulate price elastic demand. The fear of weakness may also shift official sector attitudes towards holding gold as a reserve asset relative to the currency. Many central bank feels uncomfortable with the now higher share of currency in their official reserves. The huge and ever increasing internal debt of india growing prospects of inflations. The central bank has started objective of reducing its high reserve holding of money, and it may be noteworthy that they have reported the first rise in central bank gold holding in many years. As long as currency has holding remained strong, central bank have felt no pressing need to address their high mony holding, but an eventual reserval in the money exchange rate may change the perception. The supply will also lift the gold price. Over the last 4 year , the supply despite low prices because there was a pipeline project from the 1994-96 period of higher gold price the pipline has now been almost depleted. In addition high grade to improve cash flow at low gold price. High grading increase output over the near term but ultimately reduces overall life of mine output and brings forward in time depletion dynamics. At last it shows that the price of the gold is increase or dicreases then it doesent affect on the demand and supply of commodity because it is the investment which provide always benefit to the customers, due to previous record which was explain in previous topic and cover that price cant affect on demand and supply of gold in india or any country.